| Company | State | Location | Workers | Notice date |
| Physician's Medical Center | AL | Birmingham | 1,000 | 2008-10-20 |
| Clayton Homes and CMH Manufacturing | KY | — | 170 | 2008-10-20 |
| Morning Sun | WA | Tacoma | 162 | 2008-10-23 |
| Altivity Packaging | IL | St. Charles, 1501 Indiana Avenue | 105 | 2008-10-24 |
| Northern Illinois Hospital Services | IL | Rockford, 4620 American Road | 86 | 2008-10-20 |
| Salga | IN | Fremont | 83 | 2008-10-21 |
| Saputo Cheese | VT | — | 82 | 2008-10-22 |
| Gate Gourmet | IL | Chicago, 1500 S. Lumber Street | 72 | 2008-10-23 |
| TicketsNow | IL | Crystal Lake, 265 Exchange Dr. Lower Level | 62 | 2008-10-24 |
| Archer Land Title | IN | Indianapolis | 48 | 2008-10-24 |