| Company | State | Location | Workers | Notice date |
| ATC/Vancom of Arizona | AZ | — | 953 | 2010-04-28 |
| Hospira | IL | Lake Forest, 275 North Field Drive | 514 | 2010-04-28 |
| Navistar | IN | Indianapolis | 415 | 2010-04-26 |
| ACS Government Solutions | KY | — | 286 | 2010-04-26 |
| Advocate Bethany Hospital | IL | Chicago, 3435 West Van Buren Street | 271 | 2010-04-27 |
| Honeywell | IL | Springfield, 1034 East Ash | 157 | 2010-04-28 |
| Conectiv Energy | DE | — | 150 | 2010-04-28 |
| IAP World Services | NJ | FORT DIX | 149 | 2010-05-01 |
| Amports | MD | Baltimore | 116 | 2010-04-30 |
| Philadelphia Media Holdings | NJ | CHERRY HILL | 96 | 2010-05-01 |
| Aramark Management Services at Drew University | NJ | MADISON | 94 | 2010-05-01 |
| Science Applications International | MD | Camp Springs | 82 | 2010-04-27 |
| Palombo's Med-Rite Pharmacy | NJ | NORTHFIELD | 73 | 2010-05-01 |
| Tyden Brooks Security Products Group | NJ | PHILLIPSBURG | 67 | 2010-05-01 |
| CSC | KY | — | 61 | 2010-04-30 |