| Company | State | Location | Workers | Notice date |
| Bicycle Casino | CA | Bell Gardens, Los Angeles County | 1,500 | 2021-01-04 |
| MGM National Harbor | MD | 101 MGM National Avenue Oxon Hill, MD 20745 | 518 | 2021-01-06 |
| Lucky Chances Casino | CA | Colma, San Mateo County | 489 | 2021-01-05 |
| Olympia Medical Center | CA | Los Angeles, Los Angeles County | 451 | 2021-01-08 |
| Peco Foods, Inc. Canton (Madison) | MS | — | 434 | 2021-01-08 |
| II Fornaio America | CA | Corte Madera, Marin County | 347 | 2021-01-06 |
| Hollywood Park Casino | CA | Inglewood, Los Angeles County | 328 | 2021-01-06 |
| Macy's Retail Holdings | IL | Chicago, 835 N Michigan Ave Lobby 5 | 276 | 2021-01-06 |
| Analog Devices | CA | Milpitas, Santa Clara County | 255 | 2021-01-05 |
| Peco Foods, Inc. Canton (Noxubee) | MS | — | 235 | 2021-01-08 |
| LDD Long Point Management | CA | Rancho Palos Verdes, Los Angeles County | 232 | 2021-01-06 |
| Avis Budget Car Rental | CA | Santa Clara, Santa Clara County | 229 | 2021-01-07 |
| XPO Logistics | IL | Joliet, 4005 Cedar Creek Dr | 227 | 2021-01-05 |
| Lucky Business Services, Inc. - Lucky Chances Casino | CA | Colma, San Mateo County | 220 | 2021-01-05 |
| Rosen Hotels & Resorts | FL | ORLANDO, FL, 32819 | 202 | 2021-01-08 |