| Company | State | Location | Workers | Notice date |
| Clearwater Paper | WI | Neenah | 285 | 2021-06-02 |
| Chicago Athletic Association | IL | Chicago, 12 South Michigan Avenue | 276 | 2021-06-04 |
| Katerra | AZ | Scottsdale | 251 | 2021-06-01 |
| First Student | CA | San Francisco, San Francisco County | 228 | 2021-06-03 |
| Staples Contract & Commercial | NJ | Secaucus | 194 | 2021-06-01 |
| CORE Community Organized Relief Effort | CA | Los Angeles, Los Angeles County | 192 | 2021-06-01 |
| Novartis Pharmaceuticals | NJ | East Hanover | 186 | 2021-06-01 |
| Katerra | NJ | Jersey City | 169 | 2021-06-01 |
| Hufcor | WI | Janesville | 166 | 2021-06-02 |
| Publishers Circulation Fulfillment | NJ | Perth Amboy | 148 | 2021-06-01 |
| Katerra | WA | Seattle | 117 | 2021-06-01 |
| Enterprise Leasing Company of Chicago | IL | Chicago, 10255 W Zemke Blvd | 108 | 2021-06-02 |
| Katerra | CO | Arapahoe/Douglas | 102 | 2021-06-01 |
| CORE Community Organized Relief Effort | CA | Los Angeles, Los Angeles County | 100 | 2021-06-01 |
| Kampack | NJ | Newark | 97 | 2021-06-01 |