| Company | State | Location | Workers | Notice date |
| Atlantic Express | NY | New York | 3,031 | 2010-04-29 |
| Saint Vincent Catholic Medical Centers of New York | NY | New York | 2,850 | 2010-04-15 |
| Home Services Systems | NY | Queens | 2,065 | 2010-10-14 |
| Resorts International Hotel | NJ | Atlantic City | 2,022 | 2010-10-01 |
| New York Racing Association | NY | Hempstead | 1,450 | 2010-05-24 |
| NYC Off Track Betting Corporation (Various NYC wagering sites) | NY | New York | 1,320 | 2010-01-27 |
| Takeda | IL | Deerfield, One Takeda Parkway | 1,295 | 2010-06-02 |
| Howe Developmental Center | IL | Tinley Park, 7600 West 183rd Street | 1,269 | 2010-02-02 |
| Woodbridge Logistics | NJ | Avenel | 1,114 | 2010-12-01 |
| NYC Off Track Betting Corporation (Various NYC wagering sites) | NY | New York | 1,034 | 2010-12-07 |
| Severstal International | MD | 1430 Sparrows Point Boulevard, Sparrows Point, MD | 1,012 | 2010-11-04 |
| ATC/Vancom of Arizona | AZ | — | 953 | 2010-04-28 |
| Chrysler Group | MI | Trenton | 900 | 2010-09-17 |
| Regional Elite Airline Services | KY | — | 839 | 2010-03-17 |
| Durham School Services | KS | — | 818 | 2010-03-24 |
| Health Net of the Northeast | CT | Shelton | 750 | 2010-11-04 |
| Encore Receivable Management | KS | — | 727 | 2010-11-29 |
| AJWright | IN | South Bend | 725 | 2010-12-10 |
| Cessna | KS | — | 700 | 2010-10-08 |
| MTA New York City Transit (TA) | NY | New York | 676 | 2010-04-27 |
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